• Sulfo-Cy7 NHS Ester: Advancing Quantitative NIR Imaging i...

  2025-09-22

  Explore the unique properties of Sulfo-Cy7 NHS Ester, a sulfonated near-infrared fluorescent dye, and its pivotal role in minimally invasive, quantitative imaging of biomolecule dynamics within live tissues. This article highlights the dye’s superior performance in fluorescence quenching reduction and tissue transparency imaging for cutting-edge biological research.

• Sulfo-Cy7 NHS Ester: Enabling Mechanistic Bioimaging in H...

  2025-09-19

  Explore the unique advantages of Sulfo-Cy7 NHS Ester, a sulfonated near-infrared fluorescent dye, for mechanistic studies of host–microbe interactions via advanced near-infrared fluorescent imaging. Learn how its superior water solubility and quenching resistance facilitate sensitive biomolecule conjugation in complex biological systems.

• Sulfo-Cy7 NHS Ester: Advancing Near-Infrared Imaging of B...

  2025-09-18

  Sulfo-Cy7 NHS Ester, a sulfonated near-infrared fluorescent dye, enables sensitive and hydrophilic labeling of proteins and peptides for in vivo imaging applications. This article explores its unique role in live biomolecule tracking and fluorescence quenching reduction, highlighting methodological advances for near-infrared fluorescent imaging in biological research.

• br AKT signaling is essential during early dorsal

  2025-03-03

  

  AKT signaling is essential during early dorsal patterning, neural crest induction and maturation AKT signaling modulates EMT and migration of the neural crest cells The defining feature of NC cells is their delamination from the dorsal neural epithelium. At the end of neurulation, mature premi

• It is well known that TCDD is the most potent

  2025-03-03

  

  It is well-known that TCDD is the most potent ligand of AhR and it regulates gene expression, such as CYP1A1, via activation of AhR (Mimura and Fujii-Kuriyama, 2003). Besides Tomblin et al. (2016) have recently shown that TCDD via AhR regulated L-type amino Carbamylcholine chloride transporter 1 exp

• Bufalin sale agonists simulate norepinephrine NE in

  2025-03-03

  

  α2 agonists simulate norepinephrine (NE) in binding to presynaptic surface autoreceptors, which in turn mediates feedback inhibition of NE release. Another major control mechanism for noradrenergic neurotransmission is termination of signaling by presynaptic NE transporter (NET)-mediated NE reuptake

• There is also a literature on the impact of commodity

  2025-03-03

  

  There is also a literature on the impact of commodity (consumption) taxation under imperfect competition. Besley (1989) applies a Cournot model, in which production takes place under IRS and in which free entry leads to an excessive number of firms in the market. Introducing a distortive specific co

• br Conclusion There have been multiple

  2025-03-03

  

  Conclusion There have been multiple clinical trials and pre-clinical studies that have tested the utility of 5ARIs in treating prostate disease, as summarized in Fig. 1. Inhibiting androgen action through the use of finasteride and dutasteride has been established as a valuable resource for physi

• At present drugs that specifically inhibit

  2025-03-03

  

  At present, drugs that specifically inhibit YAP activity are not available. In fact, verteporfin, which was originally described as a specific inhibitor of YAP-TEAD interaction, has been recently shown to exert its activity through selective induction of proteotoxicity rather than through YAP inhibi

• br Materials and methods br Results br Discussion Recent

  2025-03-03

  

  Materials and methods Results Discussion Recent studies have highlighted Epidermal Growth Factor (EGF), human recombinant and autophagy as novel targets for the treatment of liver fibrosis [7,14]. In this study, we demonstrated that catalpol protected the rat liver from CCl4-caused injury

• Based on the results of

  2025-03-01

  

  Based on the results of studies done to-date, there are three characteristics that make a letrozole-based protocol attractive for use in cattle: 1) it is steroid-free, 2) it is cost-effective and requires a shorter time and fewer animal handlings than conventional methods (Table 1), and 3) it may ha

• Assessment of antibiotic appropriateness is receiving

  2025-03-01

  

  Assessment of antibiotic appropriateness is receiving increased attention in the face of growing concerns about the emergence of MDROs, as well as the rise in adverse outcomes associated with antibiotic use such as C. difficile infection. In this study, 15% of cultured Gram-negative organisms met th

• br Materials and methods br Results

  2025-03-01

  

  Materials and methods Results and discussion Conclusions Acknowledgements Introduction Infections in children aged 0–21 years who reside in long-term care (LTC) facilities are common due to underlying complex medical conditions, use of invasive devices such as urinary catheters and ve

• Because of the critical roles played by

  2025-03-01

  

  Because of the critical roles played by AMPK in energy sensing and cancer cell survival, a huge number of drugs have been proposed to exert their pharmacological effects by means of AMPK activation (Kim and He, 2013). For example, metformin has been shown to activate AMPK in muscle (Sajan et al., 20

• br Experimental methods br Acknowledgments br Introduction L

  2025-03-01

  

  Experimental methods Acknowledgments Introduction Long-term potentiation (LTP) and long-term depression (LTD) at excitatory synapses are thought to underlie experience-dependent learning and memory. These synaptic plasticity mechanisms are best characterized at hippocampal CA1 synapses, whe

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