• Given the significance of methylation

  2018-11-08

  

  Given the significance of methylation/demethylation during reprogramming, we set out to investigate the function of miR-29a in regulating the iPSC methylome. Although miR-29a was shown to directly regulate both de novo DNA methyltransferases and demethylases, we found that depletion of miR-29a resul

• Aside from the benefits of the actual protocol our method

  2018-11-07

  

  Aside from the benefits of the actual protocol, our method also results in hiNSCs with multiple favorable properties including a seemingly endless capacity for self-renewal. hiNSC colonies grown on MEF feeders are approximately 50% positive for proliferation marker Ki67, a characteristic that does n

• This year is a year of extraordinary changes for this

  2018-11-07

  

  This year 2016 is a year of extraordinary changes for this journal. The – (formerly – ) has been repositioned to be a journal with international projection especially interested in addressing current issues in the frontier of knowledge in the marketing field. In this new cycle, the is fully com

• Lucas s model is one

  2018-11-07

  

  Lucas\'s model is one of the pioneers in the approach currently known as consumption-based asset pricing model. It was also the starting point to the tremendously famous Mehra and Precott (1985) paper on the equity premium puzzle. EMH and MDH have a clear relation with the rational expectation fexo

• Debt overhang constrains economic growth that leads

  2018-11-07

  

  Debt overhang constrains economic growth, that leads to less protection of human rights. According to the existing research there are 6 mechanisms through which debt can affect economic growth, the casual mechanisms are the following: i) macroeconomic instability (Dornbusch & de Pablo, 1990) (Elmend

• br Introduction Severe sepsis and

  2018-11-07

  

  Introduction Severe sepsis and shock are among the leading causes of death globally, accounting for more than 210,000 deaths annually in the United States and more than 15 million cases worldwide (Angus et al., 2001; Kumar et al., 2011; Adhikari et al., 2010). Sepsis results from a dysregulated r

• br Methods br Discussion We systematically

  2018-11-07

  

  Methods Discussion We systematically searched the literature from the last five years to identify potential blood biomarkers for cancer (Hanahan & Weinberg, 2011; Cree, 2011). The data mining process retrieved 3990 citations from the initial 19, 724 records, screening the abstracts of these ci

• Given the present data we are not able

  2018-11-07

  

  Given the present data, we are not able to explain why the left auditory ibotenic acid was overactivated during 80-Hz ASSR stimulation. However, the left and right transverse temporal gyri and left planum temporale have some differential cytoarchitectonic features (Seldon, 1981; Hutsler and Gazzani

• br Materials and Methods br Results br

  2018-11-07

  

  Materials and Methods Results Discussion In our study, we were surprised to find that the transmission is limited to F1 generation. One possible explanation for the limited transmission for enhancement of LTP is that the phenotype ends at a younger age in the offspring of FSs rats than in t

• Statins hydroxy methylglutaryl coenzyme A HMG

  2018-11-07

  

  Statins, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, include lovastatin, simvastatin, mevastatin, fluvastatin, pravastatin, atorvastatin, rosuvastatin and cerivastatin. Statins have been widely used for lowering cholesterol, but recent research reveal other roles, such as a

• oleuropein Acknowled http www apexbt com

  2018-11-07

  

  Acknowledgments S.O. and A.C.S were recipient of a fellowship of Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina). V.B., I.E.P., E.M.V., F.C. and R.A. are members of Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina). This work was partially supported by Se

• br Conflict of interest br Acknowledgements

  2018-11-07

  

  Conflict of interest Acknowledgements This work was funded by the Deutsche Forschungsgemeinschaft, project SFB TRR-58 C01, and the Department of Child and Adolescent Psychiatry, University Hospital Münster. Introduction The drive for social acceptance can promote a corresponding fear of re

• Fig details the study selection process

  2018-11-07

  

  Fig. 1 details the study selection process as recommended in the PRISMA guidelines. Characteristics of all studies discussed are presented in Tables 1–3. Characteristics of studies that are not discussed but were nevertheless analysed are presented in Tables 4–6. Tables are not provided for visual f

• Even though we aimed to include a

  2018-11-07

  

  Even though we aimed to include a comprehensive sample with a well-validated experimental task, several limitations of this Elacridar Supplier study need to be mentioned. First, we had to collapse across conditions within the emotional face-processing task to have enough power left for the habituat

• br Acknowledgements br Introduction The past decade has seen

  2018-11-07

  

  Acknowledgements Introduction The past decade has seen dramatic increases in our knowledge about the organization of the developing glut1 (Aslin et al., 2015). However, the majority of these investigations are targeted at understanding how development occurs in specific domains (e.g., how doe

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