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br Biogeography and botanical description Based
2018-11-06
Biogeography and botanical description Based on both historical literature [1,2,5], and recent analysis of random amplified polymorphic DNA [6], inter simple sequence repeats [7] and amplified fragment length polymorphisms [8] molecular analyses, eastern India (including the states of Orissa, Wes
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Environmental samples may contain mixed populations of STEC
2018-11-06
Environmental samples may contain mixed populations of STEC strains, many of which could share O-type domoic acid with a variety of H-antigens. It has been suggested that identifying fliC gene type may be helpful for detection of pathogenic STEC strains. Several H-types including H-, H2, H7, H8, H1
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br Conclusion Pu erh extracts
2018-11-06
Conclusion Pu-erh extracts showed a strong protection effect against the hepatic damage by oxidative stress. The protection mechanism of Pu-erh extracts is confirmed in the study via the activation of the hepatic antioxidant system and the reversal of lipid peroxidation. In addition, Pu-erh tea e
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Because ESCs grow as colonies juxtacrine signaling could als
2018-11-06
Because ESCs grow as colonies, juxtacrine signaling could also presumably play a growth-supportive role. Todorova et al. used pharmacological blockers of gap junctional communication and Connexin-43 small-interfering RNA to inhibit signaling via gap junctions in mESCs (Todorova et al., 2008). They d
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Although Sca is another conserved marker present
2018-11-06
Although Sca-1 is another conserved marker present in both stromal and epithelial SCs of many tissues, including hematopoietic Phos-tag cost (Spangrude et al., 1988), mouse incisor pulp progenitor cells (Balic et al., 2010), lung (Kim et al., 2005), prostate (Lawson et al., 2007), and pancreas (Rov
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Previous in vitro characterization of compensatory TSC
2018-11-06
Previous in vitro characterization of compensatory TSC differentiation was performed at 20% O2 with a dose of benzopyrene or hyperosmolar stress that activated maximal stress enzyme (Zhong et al., 2010; Xie et al., 2010). When O2 levels are optimized, the highest growth and the least stress (activat
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br Materials and methods The PQ embryos from
2018-11-06
Materials and methods The PQ embryos from in vitro fertilization were donated, and the fetal membranes were collected in accord with the INPER Ethics Committee (212250-21071) as well as the Guidelines for the Conduct of hESC Research (ISSCR, 2006). The hAEC were isolated and cultured from human
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Myriocin br Resource table Resource details Following their
2018-11-06
Resource table: Resource details Following their mechanical isolation from day 7 blastocysts, the inner cell masses (ICM) were seeded individually onto the feeder layers. After 2days of incubation, most of the ICMs were found attached to the feeder cells. The cultures were allowed to grow for 8–
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Introduction The generation of an organ
2018-11-06
Introduction The generation of an organ requires strict control of the number and identity of cells generated during development. Zac1 (also known as Plagl1) belongs to an imprinted gene network (IGN), which has been shown to control embryonic growth (Varrault et al., 2006). Accordingly, Zac1 knock
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Recent methods of reprogramming human
2018-11-06
Recent methods of reprogramming human fibroblasts to iNSCs employed genome-integrating lentiviral or retroviral vectors (Kumar et al., 2012; Ring et al., 2012), which may produce insertional mutations and residual or reactivation of transgenes. We used oriP/EBNA-1 episomal vectors to deliver reprogr
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The karyotype of the BIOT
2018-11-06
The karyotype of the BIOT-0708-EHMT1 iPSC line was determined with Giemsa-banding, proving normal diploid 46, XX karyotype, without any detectable abnormalities (Fig. 1B). In parallel, the pathogenic NM_024757.4(EHMT1):c.3413G>A mutation was confirmed by Sanger sequencing in the newly established i
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T cell insufficiency is associated with other congenital thy
2018-11-06
T cell insufficiency is associated with other congenital thymic hypoplasias, such as DiGeorge syndrome (Jerome and Papaioannou, 2001), age-related thymus atrophy, or cytoablative therapy-induced thymic involution. In the last case, patients undergoing high-dose chemotherapy often experience chronic
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Here we used iPSCs to generate cardiomyocytes by reprogrammi
2018-11-06
Here, we used iPSCs to generate cardiomyocytes by reprogramming skin fibroblasts from two patients carrying dissimilar LQTS mutations. Associated with LQT2, HERG-A422T produces trafficking-defective HERG K+ Sulfo-NHS-LC-Biotin (Kv 11.1) that decrease the rapidly activating delayed rectifier current
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Main Text In this issue of Stem Cell Reports two
2018-11-05
Main Text In this issue of Stem Cell Reports, two critically important studies describe negative results of a neural stem cell (NSC) product (HuCNS-SC) intended for clinical use in a model of cervical spinal cord injury (SCI) (Anderson et al., 2017) and in a model of Alzheimer’s disease (Marsh et a
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br The association between migration and health The event of
2018-11-05
The association between Toyocamycin and health The event of migration is known to be associated with stress and processes that may influence health, such as increased stress levels, disrupted social ties, diminished social support and social isolation (Deri, 2005; Jasso, Massey, Rosenzweig, & S
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