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          It is noteworthy that in a recent study Le2019-05-17  It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex 
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          Contributors Conflicts of interest br Acknowledgments This2019-05-17  Contributors Conflicts of interest Acknowledgments This research was funded by the Bill & Melinda Gates Foundation. The views expressed herein are those SIRT1/2 Inhibitor IV of the authors and do not necessarily represent the official policy or position of the Bill & Melinda Gates Foundation, I 
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          Na defini o da Secretaria Nacional de Pol ticas de2019-05-16  Na definição da Secretaria Nacional de Políticas de Promoção da Igualdade Racial, vinculada atualmente ao Ministério dos Direitos Humanos do governo federal, as ações afirmativas são políticas públicas que têm como objetivo As shown in correção de desigualdades raciais acumuladas ao longo dos anos 
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          Introduction The World health organization WHO defines acute2019-05-16  Introduction The 2008 World health organization (WHO) defines acute leukemias with ambiguous lineage (ALAL) as those leukemias which show no clear differentiation towards either myeloid or lymphoid lineage. It includes acute undifferentiated leukemias which express no specific markers for both line 
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          br Conflict of interest br2019-05-16  Conflict of interest Introduction Far-field sensing of the atrial electrogram by a ventricular inhibited (VVI) pacemaker is a rare but potentially catastrophic phenomenon if there is no escape rhythm [1–3]. In this setting, the tip of the pacemaker lead is usually located in close proximity to 
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          ache inhibitors br Conflict of interest br2019-05-16  Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in 
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          Common and rare SCN A2019-05-16  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian 
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          HBeAg positive patients older than years with2019-05-16  HBeAg-positive patients older than 40 years with persistently high or high to normal ALT levels may be diagnosed with significant hepatic necroinflammation or fibrosis. During treatment, the clinical significance of timing of HBeAg loss or seroconversion remains unclear. However, a longer duration o 
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          The measurement of the PPI of DP2019-05-16  The measurement of the PPI of DP following entrainment pacing usually consists of measuring the interval between the last capturing stimulus and the next DP. This technique is generally based on the assumption that, in the presence of 1:1 capture, pacing depolarizes the zone of slow conduction in th 
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          In summary programmed long AVD prolonged2019-05-16  In summary, programmed long AVD, prolonged VA conduction time caused by anti-arrhythmic medication, and the rate of ELT (110bpm, below the upper tracking rate of 120bpm) were the reason ELT continued even in the presence of a programmed ELT termination algorithm. Physicians who manage patients with 
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          This patient s shortest R R interval on ECG was2019-05-16  This patient\'s shortest R–R interval on ECG was about 200ms (300bpm), which indicated high risk of sudden cardiac death. The patient underwent catheter ablation. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias [1], which include accessory pathway-mediated arr 
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          br Materials and methods br Results br Discussion2019-05-16  Materials and methods Results Discussion Although EMT can be induced by different factors under exogenous stimuli, it is intriguing to consider whether these EMT inducers are redundant because of their mechanistic similarity in EMT induction. The interplay and underlying mechanism between E 
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          ECG changes emerged when creating a substrate map of2019-05-16  ECG changes emerged when creating a substrate map of the LV (Fig. 2A), near the inferior mitral valve. A long transseptal sheath was introduced into the LV under intracardiac echocardiography guidance without causing an air-embolism. While performing the LV substrate mapping, the long transseptal sh 
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          El valor testimonial de Tampico sin2019-05-16  El valor testimonial de Tampico sin duda desborda las intenciones de su exquisito autor, quien se sentía más glycine receptors gusto describiendo las finas maderas de los muebles de su casa, que padeciendo el asedio de la incomodidad, el calor y los mosquitos de los pueblos del Golfo de México. Jose 
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          In the context of cataract surgery Nathan Congdon2019-05-16  In the context of cataract surgery, Nathan Congdon and colleagues (August, p e37) propose the possibility of using early postoperative assessment of all patients or late assessment only of those who return for follow-up without additional prompting as practicable methods to improve long-term patient 
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